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Literature summary for 2.5.1.18 extracted from

  • Pflugmacher, S.; Wiegand, C.; Werner, S.; Schroeder, H.; Kankaanpaeae, H.
    Activity and substrate specificity of cytosolic and microsomal glutathione S-transferase in australian black tiger prawns (Penaeus monodon) after exposure to cyanobacterial toxins (2005), Environ. Toxicol., 20, 301-307.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information low cyanobacterial toxin content was correlated with high elevation of enzymes and high toxin content with low elevation of isozymes Penaeus monodon

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Penaeus monodon 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glutathione + microcystin-LR Penaeus monodon cyanobacterial toxins are hypothesized to contribute to the mortality of prawns, many aquatic organisms have the possibility of detoxifying cyanobacterial toxins, e.g. nodularin or microcystin-LR, via conjugation to glutathione ?
-
?
glutathione + nodularin Penaeus monodon cyanobacterial toxins are hypothesized to contribute to the mortality of prawns, many aquatic organisms have the possibility of detoxifying cyanobacterial toxins, e.g. nodularin or microcystin-LR, via conjugation to glutathione ?
-
?

Organism

Organism UniProt Comment Textmining
Penaeus monodon
-
isozymes of classes mu, pi, theta, alpha, and tau
-

Source Tissue

Source Tissue Comment Organism Textmining
head
-
Penaeus monodon
-
hepatopancreas
-
Penaeus monodon
-
additional information isozyme-dependent tissue-specific substrate specificity, overview Penaeus monodon
-
muscle
-
Penaeus monodon
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutathione + 1,2-dichloro-4-nitrobenzene substrate of the mu class isozyme Penaeus monodon ?
-
?
glutathione + 1,2-epoxy-3-(p-nitrophenoxy)-propane substrate of the theta class isozyme Penaeus monodon ?
-
?
glutathione + 1-chloro-2,4-dinitrobenzene substrate of mu, pi, theta, alpha, and tau class isozymes Penaeus monodon chloride + 2,4-dinitrophenyl-glutathione
-
?
glutathione + 4-nitrobenzyl chloride substrate of the alpha class isozyme Penaeus monodon chloride + 4-nitrobenzyl-glutathione
-
?
glutathione + ethacrynic acid substrate of the pi class isozyme Penaeus monodon ?
-
?
glutathione + fluorodifen substrate of the tau class isozyme Penaeus monodon ?
-
?
glutathione + microcystin-LR cyanobacterial toxins are hypothesized to contribute to the mortality of prawns, many aquatic organisms have the possibility of detoxifying cyanobacterial toxins, e.g. nodularin or microcystin-LR, via conjugation to glutathione Penaeus monodon ?
-
?
glutathione + microcystin-LR a cyanobacterial toxin Penaeus monodon ?
-
?
glutathione + nodularin cyanobacterial toxins are hypothesized to contribute to the mortality of prawns, many aquatic organisms have the possibility of detoxifying cyanobacterial toxins, e.g. nodularin or microcystin-LR, via conjugation to glutathione Penaeus monodon ?
-
?
glutathione + nodularin a cyanobacterial toxin Penaeus monodon ?
-
?
additional information isozyme-dependent tissue-specific substrate specificity, overview Penaeus monodon ?
-
?

Synonyms

Synonyms Comment Organism
glutathione S-transferase
-
Penaeus monodon
GST
-
Penaeus monodon