Protein Variants | Comment | Organism |
---|---|---|
Y81D | contrary to wild-type, reaction of (Z)-ethynyldimethylallyl diphosphate plus isopentenyl diphosphate yields a mixture of products ethynylgeranyl, ethynylfarnesyl, and ethynylgeranylgeranyl diphosphates | Sus scrofa |
Y81D | contrary to wild-type, reaction of (Z)-ethynyldimethylallyl diphosphate plus isopentenyl diphosphate yields a mixture of products ethynylgeranyl, ethynylfarnesyl, and ethynylgeranylgeranyl diphosphates | Geobacillus stearothermophilus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Geobacillus stearothermophilus | - |
- |
- |
Sus scrofa | - |
bifunctional geranyl diphosphate synthase EC 2.5.1.1 and farnesyl diphosphate synthase EC 2.5.1.10 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(E)-ethynyldimethylallyl diphosphate + isopentenyl diphosphate | - |
Geobacillus stearothermophilus | (E)-ethynylfarnesyl diphosphate + diphosphate | double condensation product. Yield is 0.8% E-ethynylfarnesyl diphosphate, compared with 100% for the reaction of dimethylallyl diphosphate with isopentenyl diphosphate | ? | |
(Z)-ethynyldimethylallyl diphosphate + isopentenyl diphosphate | - |
Sus scrofa | (Z)-ethynylfarnesyl diphosphate + diphosphate | sole product with wild-type, yield is 21.9% Z-ethynylfarnesyl diphosphate, compared with 100% for the reaction of dimethylallyl diphosphate with isopentenyl diphosphate | ? | |
(Z)-ethynyldimethylallyl diphosphate + isopentenyl diphosphate | - |
Geobacillus stearothermophilus | (Z)-ethynylfarnesyl diphosphate + diphosphate | sole product with wild-type, yield is 88.8% Z-ethynylfarnesyl diphosphate, compared with 100% for the reaction of dimethylallyl diphosphate with isopentenyl diphosphate. Mutant Y81D yields products ethynylgeranyl, ethynylfarnesyl, and ethynylgeranylgeranyl diphosphates | ? | |
vinyldimethylallyl diphosphate + isopentenyl diphosphate | - |
Geobacillus stearothermophilus | vinylfarnesyl diphosphate + diphosphate | sole product, yield is 29.9% vinylfarnesyl diphosphate, compared with 100% for the reaction of dimethylallyl diphosphate with isopentenyl diphosphate | ? | |
vinyldimethylallyl diphosphate + isopentenyl diphosphate | - |
Sus scrofa | vinylgeranyl diphosphate + vinylfarnesyl diphosphate + diphosphate | 14.3% vinylgeranyl diphosphate plus 23.3% vinylfarnesyl diphosphate, compared with 100% for the reaction of dimethylallyl diphosphate with isopentenyl diphosphate | ? |