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Literature summary for 2.4.3.4 extracted from

  • Wen, K.; Sung, P.; Hsieh, S.; Chou, Y.; Lee, O.; Wu, C.; Wang, P.
    alpha2,3-Sialyltransferase type I regulates migration and peritoneal dissemination of ovarian cancer cells (2017), Oncotarget, 8, 29013-29027 .
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine the enzyme is a prognostic factor for migration and peritoneal dissemination of human ovarian cancer cells. High enzyme expression is associated with advanced stage epithelial ovarian cancer Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
soyasaponin I competitive inhibitor Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
epithelial ovarian cancer cell
-
Homo sapiens
-
ES-2 cell
-
Homo sapiens
-
MOSEC cell
-
Homo sapiens
-
OVCAR-3 cell
-
Homo sapiens
-

Subunits

Subunits Comment Organism
? x * 37000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
alpha2,3-sialyltransferase type I
-
Homo sapiens
ST3GalI
-
Homo sapiens

General Information

General Information Comment Organism
physiological function the enzyme regulates ovarian cancer cell migration and peritoneal dissemination via epidermal growth factor receptor signaling Homo sapiens