Literature summary for 2.4.3.4 extracted from

Perez-Garay, M.; Arteta, B.; Pages, L.; de Llorens, R.; de Bolos, C.; Vidal-Vanaclocha, F.; Peracaula, R.
alpha2,3-Sialyltransferase ST3Gal III modulates pancreatic cancer cell motility and adhesion in vitro and enhances its metastatic potential in vivo (2010), PLoS ONE, 5, e12524.

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
CAPAN-1 cell	-	Homo sapiens	-
MDA-Panc-28 cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
alpha-2,3-sialyltransferase	-	Homo sapiens
ST3Gal III	isoform	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	the enzyme modulates pancreatic cancer cell motility and adhesion in vitro and enhances its metastatic potential in vivo. Isoform ST3Gal III increases de novo expression of SLex by enzymatic competition, enhances pancreatic adenocarcinoma cells adhesion to rh-E-selectin, and increases tumour cell adhesion to HSE cells	Homo sapiens

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Release 2023.1 (January 2023)