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Literature summary for 2.4.2.8 extracted from

  • Somoza, J.R.; Chin, M.S.; Wang, C.C.; Fletterick, R.J.
    Crystal structure of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from the protozoan parasite Tritrichomonas foetus (1996), Biochemistry, 35, 7032-7040.
    View publication on PubMed

Application

Application Comment Organism
medicine target for antiparasite drug design Tritrichomonas suis

Crystallization (Commentary)

Crystallization (Comment) Organism
crystallization and X-ray structure determination and analysis, 1 molecule of GMP bound per dimer Tritrichomonas suis

Organism

Organism UniProt Comment Textmining
Tritrichomonas suis
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-
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Reaction

Reaction Comment Organism Reaction ID
IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate active site structure Tritrichomonas suis