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Literature summary for 2.4.2.4 extracted from
- Suppression of thymidine phosphorylase expression by promoter methylation in human cancer cells lacking enzyme activity (2008), Cancer Chemother. Pharmacol., 62, 85-96.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | thymidine phosphorylase promoter methylation is a mechanism for down-regulation of enzyme expression in cancer cells | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| DLD-1 cell | - |
Homo sapiens | - |
| HT-29 cell | - |
Homo sapiens | - |
| MDA-MB-231 cell | - |
Homo sapiens | - |
| RCC 786-O cell | - |
Homo sapiens | - |
| SK-BR-3 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| thymidine + phosphate | - |
Homo sapiens | thymine + 2-deoxy-D-ribose 1-phosphate | - |
? |  |
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Release 2023.1 (January 2023)
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