Literature summary for 2.4.2.4 extracted from

De Bruin, M.; Van Capel, T.; Smid, K.; Fukushima, M.; Hoekman, K.; Pinedo, H.M.; Peters, G.J.
The effect of fluoropyrimidines with or without thymidine phosphorylase inhibitor on the expression of thymidine phosphorylase (2004), Eur. J. Pharmacol., 491, 93-99.

Search for more literature for 2.4.2.4

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	no inhibition by 5'-deoxy-5-fluorouridine	Homo sapiens
thymidine phosphorylase inhibitor	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
colonic cancer cell	WiDR, HT29 and Lovo	Homo sapiens	-
HT-29 cell	-	Homo sapiens	-
LoVo cell	-	Homo sapiens	-
WiDr cell	-	Homo sapiens	-

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.00002	-	thymidine phosphorylase inhibitor	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)