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Literature summary for 2.4.2.30 extracted from
- The 40 kDa carboxy-terminal domain of poly(ADP-ribose) polymerase-1 forms catalytically competent homo- and heterodimers in the absence of DNA (2004), J. Mol. Biol., 336, 105-114.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| 40 kDa carboxy-terminal catalytic fragment of PARP-1 comprising residues 6541014 is genetically expressed in insect cells (Spodoptera frugiperda, Sf9) | Gallus gallus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Gallus gallus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Gallus gallus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NAD+ + poly(ADP-ribose) polymerase-1 | the 40 kDa CD fragment of avian PARP-1 efficiently catalyzes a covalent auto-poly-(ADP-ribosyl)ation reaction via an intermolecular mechanism that is completely independent of DNA | Gallus gallus | nicotinamide + (ADP-ribosyl)-poly(ADP-ribose) polymerase-1 | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PARP-1 | - |
Gallus gallus |
| poly(ADP-ribose) polymerase-1 | - |
Gallus gallus |
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Release 2023.1 (January 2023)
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