Literature summary for 2.4.2.3 extracted from

Renck, D.; Santos, A.A.; Machado, P.; Petersen, G.O.; Lopes, T.G.; Santos, D.S.; Campos, M.M.; Basso, L.A.
Human uridine phosphorylase-1 inhibitors: a new approach to ameliorate 5-fluorouracil-induced intestinal mucositis (2014), Invest. New Drugs, 32, 1301-1307.

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Inhibitors

Inhibitors	Comment	Organism	Structure
5-(phenylthio) acyclouridine	-	Rattus norvegicus
5-benzylacyclourine	-	Rattus norvegicus
6-hydroxy-4-methyl-1H-pyridin-2-one-3-carbonitrile	-	Rattus norvegicus
6-hydroxy-5-(((2-hydroxyethyl) amino) methyl)-4-methyl-1H-pyridin-2-one-3-carbonitrile	-	Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
uridine + phosphate	Rattus norvegicus	-	uracil + alpha-D-ribose 1-phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	Q499V1	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
uridine + phosphate	-	Rattus norvegicus	uracil + alpha-D-ribose 1-phosphate	-	?

Synonyms

Synonyms	Comment	Organism
UP1	-	Rattus norvegicus
uridine phosphorylase-1	-	Rattus norvegicus

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Release 2023.1 (January 2023)