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Literature summary for 2.4.2.29 extracted from

  • Garcia, G.A.; Koch, K.A.; Chong, S.
    tRNA-guanine transglycosylase from Escherichia coli. Overexpression, purification and quaternary structure (1993), J. Mol. Biol., 231, 489-497.
    View publication on PubMed
Search for more literature for 2.4.2.29

Cloned(Commentary)

Cloned (Comment) Organism
-
 Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
dimethylsuberimidate inactivates by cross-linking, tRNA protects Escherichia coli
ethylacetimidate
-
 Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
guanine34 in tRNA + 7-aminomethyl-7-carbaguanine Escherichia coli the enzyme is responsible for the posttranscriptional modification of specific tRNAs (Asn, Asp, His and Tyr) with queuine. The enzyme catalyzes base exchange of guanosine34 with 7-aminomethyl-7-deazaguanine 7-aminomethyl-7-carbaguanine34 in tRNA + guanine
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
guanine34 in tRNA + 7-aminomethyl-7-carbaguanine
-
 Escherichia coli 7-aminomethyl-7-carbaguanine34 in tRNA + guanine
-
 ?
guanine34 in tRNA + 7-aminomethyl-7-carbaguanine the enzyme is responsible for the posttranscriptional modification of specific tRNAs (Asn, Asp, His and Tyr) with queuine. The enzyme catalyzes base exchange of guanosine34 with 7-aminomethyl-7-deazaguanine Escherichia coli 7-aminomethyl-7-carbaguanine34 in tRNA + guanine
-
 ?