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Literature summary for 2.4.2.28 extracted from

  • Slominska, E.M.; Kalsi, K.K.; Yacoub, M.H.; Smolenski, R.T.
    The role of 5'-deoxy-5'-methyl thioadenosine phosphorylase in cardiac adenosine breakdown and adenine production (2000), Adv. Exp. Med. Biol., 486, 159-162.
    View publication on PubMed
Search for more literature for 2.4.2.28

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.014
-
 5'-deoxy-5'-methylthioadenosine
-
 Homo sapiens
0.184
-
 adenosine
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5'-deoxy-5'-methylthioadenosine + phosphate Homo sapiens involved in cardiac purine breakdown during ischemia adenine + 5-methylthio-D-ribose 1-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
 Wistar
-
Rattus norvegicus Wistar
-
 Wistar
-
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart left ventricular specimen Homo sapiens
-
heart left ventricular specimen Rattus norvegicus
-
heart left ventricular specimen Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Homo sapiens
additional information
-
-
 Rattus norvegicus
additional information
-
-
 Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5'-deoxy-5'-methylthioadenosine + phosphate
-
 Homo sapiens adenine + 5-methylthio-D-ribose 1-phosphate
-
 ?
5'-deoxy-5'-methylthioadenosine + phosphate
-
 Rattus norvegicus adenine + 5-methylthio-D-ribose 1-phosphate
-
 ?
5'-deoxy-5'-methylthioadenosine + phosphate
-
 Sus scrofa adenine + 5-methylthio-D-ribose 1-phosphate
-
 ?
5'-deoxy-5'-methylthioadenosine + phosphate involved in cardiac purine breakdown during ischemia Homo sapiens adenine + 5-methylthio-D-ribose 1-phosphate
-
 ?
5'-deoxy-5'-methylthioadenosine + phosphate
-
 Rattus norvegicus Wistar adenine + 5-methylthio-D-ribose 1-phosphate
-
 ?
adenosine + phosphate
-
 Homo sapiens adenine + D-ribose 1-phosphate
-
 ?
adenosine + phosphate
-
 Rattus norvegicus adenine + D-ribose 1-phosphate
-
 ?
adenosine + phosphate
-
 Sus scrofa adenine + D-ribose 1-phosphate
-
 ?
adenosine + phosphate
-
 Rattus norvegicus Wistar adenine + D-ribose 1-phosphate
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens
37
-
 assay at Rattus norvegicus
37
-
 assay at Sus scrofa