Activating Compound | Comment | Organism | Structure |
---|---|---|---|
putrescine | no effect | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-Deoxyribose 1-phosphate | - |
Rattus norvegicus | |
adenine | - |
Rattus norvegicus | |
fructose 1-phosphate | - |
Rattus norvegicus | |
guanine | - |
Rattus norvegicus | |
L-methionine | weak | Rattus norvegicus | |
additional information | no inhibition by EDTA, putrescine, cadaverine | Rattus norvegicus | |
ribose 1-phosphate | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | no requirement for metal ion, e.g. Mg2+, Mn2+ or Ca2+ | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
from lung | Rattus norvegicus |
partial | Rattus norvegicus |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
S-methyl-5'-thioadenosine + phosphate = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate | phosphorolytic mechanism | Rattus norvegicus | |
S-methyl-5'-thioadenosine + phosphate = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate | equilibrium-ordered reaction, 5'-methylthioadenosine is the first substrate to bind and 5-methylthioribose 1-phosphate is the first product to be released | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | low activity | Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
lung | - |
Rattus norvegicus | - |
additional information | wide tissue distribution | Rattus norvegicus | - |
spleen | - |
Rattus norvegicus | - |
testis | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
kinetics | Rattus norvegicus |
Storage Stability | Organism |
---|---|
-70°C, stable for at least 4 months | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5'-methylthioadenosine + phosphate | - |
Rattus norvegicus | adenine + 5-methylthio-D-ribose 1-phosphate | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | 8 | - |
Rattus norvegicus |