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Literature summary for 2.4.2.26 extracted from

  • Götting, C.; Kuhn, J.; Brinkmann, T.; Kleesiek, K.
    Xylosyltransferase activity in seminal plasma of infertile men (2002), Clin. Chim. Acta, 317, 199-202.
    View publication on PubMed
Search for more literature for 2.4.2.26

Application

Application Comment Organism
medicine monitoring of the seminal plasma for enzyme activity is proposed to be an advantegeous additional biochemical parameter to improve in vitro fertilization methods, because the activity is reduced in seminal plasma of infertile men Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens enzyme activity in seminal plasma of infertile men is significantly reduced ?
-
 ?
UDP-alpha-D-xylose + [protein]-L-serine Homo sapiens enzyme initiates the biosynthesis of glycosaminoglycan lateral chains in proteoglycans by transfer of xylose from UDP-xylose to specific serine residues of the core protein UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information enzyme activity in seminal plasma of infertile men is significantly reduced Homo sapiens
-
seminal plasma of healthy and infertile men with oligo-, astheno- or teratozoospermia, and of men after vasectomy Homo sapiens
-
seminal vesicle highest activity Homo sapiens
-
serum of healthy and infertile men with oligo-, astheno- or teratozoospermia, and of men after vasectomy Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme activity in seminal plasma of infertile men is significantly reduced Homo sapiens ?
-
 ?
UDP-alpha-D-xylose + [protein]-L-serine transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate Homo sapiens UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
UDP-alpha-D-xylose + [protein]-L-serine enzyme initiates the biosynthesis of glycosaminoglycan lateral chains in proteoglycans by transfer of xylose from UDP-xylose to specific serine residues of the core protein Homo sapiens UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
UDP-D-xylose + bikunin recombinant bikunin Homo sapiens UDP + D-xylosyl-bikunin bound to serine residue ?

Synonyms

Synonyms Comment Organism
XT
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
 assay at Homo sapiens