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Literature summary for 2.4.2.12 extracted from

  • Rongvaux, A.; Shea, R.J.; Mulks, M.H.; Gigot, D.; Urbain, J.; Leo, O.; Andris, F.
    Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis (2002), Eur. J. Immunol., 32, 3225-3234.
    View publication on PubMed
Search for more literature for 2.4.2.12

Cloned(Commentary)

Cloned (Comment) Organism
pre-B-cell colony enhancing factor Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00124
-
 nicotinamide
-
 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Mus musculus 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate Mus musculus pre-B-cell colony enhancing factor nicotinamide D-ribonucleotide + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 identified as pre-B-cell colony-enhancing factor
-

Source Tissue

Source Tissue Comment Organism Textmining
lymphocyte
-
 Mus musculus
-
additional information ubiquitous in all tissues Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate
-
 Mus musculus nicotinamide D-ribonucleotide + diphosphate
-
 ?
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate pre-B-cell colony enhancing factor Mus musculus nicotinamide D-ribonucleotide + diphosphate
-
 ?