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Literature summary for 2.4.2.1 extracted from

  • Bagarolo, M.L.; Porcelli, M.; Martino, E.; Feller, G.; Cacciapuoti, G.
    Multiple disulfide bridges modulate conformational stability and flexibility in hyperthermophilic archaeal purine nucleoside phosphorylase (2015), Biochim. Biophys. Acta, 1854, 1458-1465.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(lambdaDE3) cells Saccharolobus solfataricus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5'-deoxy-5'-methylthioadenosine + phosphate Saccharolobus solfataricus
-
adenine + 5-deoxy-5-methylthio-alpha-D-ribose 1-phosphate
-
?
5'-deoxy-5'-methylthioadenosine + phosphate Saccharolobus solfataricus P2
-
adenine + 5-deoxy-5-methylthio-alpha-D-ribose 1-phosphate
-
?

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus Q97W94
-
-
Saccharolobus solfataricus P2 Q97W94
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5'-deoxy-5'-methylthioadenosine + phosphate
-
Saccharolobus solfataricus adenine + 5-deoxy-5-methylthio-alpha-D-ribose 1-phosphate
-
?
5'-deoxy-5'-methylthioadenosine + phosphate
-
Saccharolobus solfataricus P2 adenine + 5-deoxy-5-methylthio-alpha-D-ribose 1-phosphate
-
?

Subunits

Subunits Comment Organism
hexamer
-
Saccharolobus solfataricus

Synonyms

Synonyms Comment Organism
5'-deoxy-5'-methylthioadenosine phosphorylase II
-
Saccharolobus solfataricus
MTAPII
-
Saccharolobus solfataricus
SSO2343 locus name Saccharolobus solfataricus