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BRENDA support

Literature summary for 2.4.2.1 extracted from

  • Aberg, A.M.; Ronquist, G.; Haney, M.; Waldenstrom, A.
    Effects of some modulators on purine nucleoside phosphorylase activity in myocardial tissue (2010), Scand. J. Clin. Lab. Invest., 70, 8-14.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
EDTA
-
Sus scrofa
staurosporine stimulation Sus scrofa
thapsigargin stimulation Sus scrofa

Application

Application Comment Organism
analysis determination of enzymic activity using commercially available substrate 2-amino-6-mercapto-7-methylpurine ribonucleoside and photometric assessment of the reaction Sus scrofa

Inhibitors

Inhibitors Comment Organism Structure
adenosine 1 mM, about 20% inhibition Sus scrofa
EGTA
-
Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart similar activity for ischemic tissue and normal tissue of hte same heart Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-amino-6-mercapto-7-methylpurine ribonucleoside + phosphate
-
Sus scrofa alpha-D-ribose 1-phosphate + 2-amino-6-mercapto-7-methylpurine
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
-
Sus scrofa

pH Range

pH Minimum pH Maximum Comment Organism
6 6.8
-
Sus scrofa