Cloned (Comment) | Organism |
---|---|
DNA and amino acid sequence determination and analysis, stable expression in and functional complementation of Vero cells, which renders the cells resistant against the toxin | Mus musculus |
DNA and amino acid sequence determination and analysis, stable expression in and functional complementation of Vero cells, which renders the cells resistant against the toxin | Canis lupus familiaris |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | enzyme is responsible for production of Forssman glycolipid, the enzyme modifies the Shiga toxin receptor glycolipids, e.g. globotriaosylceramide, to Forssman glycolipid, which results in highly decreased susceptibility for Shiga toxin, the enzyme expression level is directly related to the level of sensitivity for the cytotoxin | ? | - |
? | |
additional information | Canis lupus familiaris | enzyme is responsible for production of Forssman glycolipid, the enzyme modifies the Shiga toxin receptor glycolipids, e.g. globotriaosylceramide, to Forssman glycolipid, which results in highly decreased susceptibility for Shiga toxin, the enzyme expression level is directly related to the level of sensitivity for the cytotoxin | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Canis lupus familiaris | - |
- |
- |
Mus musculus | - |
- |
- |
no activity in Homo sapiens | - |
due to natively occurring inactive gene mutant | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme is responsible for production of Forssman glycolipid, the enzyme modifies the Shiga toxin receptor glycolipids, e.g. globotriaosylceramide, to Forssman glycolipid, which results in highly decreased susceptibility for Shiga toxin, the enzyme expression level is directly related to the level of sensitivity for the cytotoxin | Mus musculus | ? | - |
? | |
additional information | enzyme is responsible for production of Forssman glycolipid, the enzyme modifies the Shiga toxin receptor glycolipids, e.g. globotriaosylceramide, to Forssman glycolipid, which results in highly decreased susceptibility for Shiga toxin, the enzyme expression level is directly related to the level of sensitivity for the cytotoxin | Canis lupus familiaris | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Forssman synthetase | - |
Mus musculus |
Forssman synthetase | - |
Canis lupus familiaris |
FS | - |
Mus musculus |
FS | - |
Canis lupus familiaris |