Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | about 30% inhibition at 0.4 mM | Helicobacter pylori | |
dGDP | about 40% inhibition at 0.4 mM | Helicobacter pylori | |
dGDP | about 76% inhibition at 0.4 mM | Homo sapiens | |
GDP | about 78% inhibition at 0.4 mM | Helicobacter pylori | |
GDP | about 80% inhibition at 0.4 mM | Homo sapiens | |
GDP-6-amino-beta-L-fucose | about 45% inhibition at 1 mM | Helicobacter pylori | |
GDP-6-amino-beta-L-fucose | 78% inhibition at 0.4 mM | Homo sapiens | |
GTP | about 70% inhibition at 0.4 mM | Helicobacter pylori | |
GTP | about 80% inhibition at 0.4 mM | Homo sapiens | |
IDP | about 60% inhibition at 0.4 mM | Helicobacter pylori | |
IDP | about 30% inhibition at 0.4 mM | Homo sapiens | |
L-fucose | about 20% inhibition at 0.4 mM | Helicobacter pylori | |
additional information | not inhibited by GMP | Helicobacter pylori | |
additional information | not inhibited by L-fucose, GMP and ADP | Homo sapiens | |
[1-(beta-D-fucopyranosyl)-1H-1,2,3-triazole-4-yl]methylguanosine diphosphate | about 70% inhibition at 0.4 mM | Homo sapiens | |
[1-(beta-D-fucopyranosyl)-1H-1,2,3-triazole-4-yl]methylguanosinediphosphate | about 74% inhibition at 0.4 mM | Helicobacter pylori | |
[1-(beta-D-galactopyranosyl)-1H-1,2,3-triazole-4-yl] methylguanosine diphosphate | about 76% inhibition at 0.4 mM | Helicobacter pylori | |
[1-(beta-D-galactopyranosyl)-1H-1,2,3-triazole-4-yl] methylguanosine diphosphate | about 73% inhibition at 0.4 mM | Homo sapiens | |
[1-(beta-D-lactosyl)-1H-1,2,3-triazole-4-yl]methylguanosine diphosphate | about 60% inhibition at 0.4 mM | Helicobacter pylori | |
[1-(beta-D-lactosyl)-1H-1,2,3-triazole-4-yl]methylguanosine diphosphate | about 45% inhibition at 0.4 mM | Homo sapiens | |
[1-(beta-L-fucopyranosyl)-1H-1,2,3-triazole-4-yl]methylguanosine diphosphate | about 58% inhibition at 0.4 mM | Helicobacter pylori | |
[1-(beta-L-fucopyranosyl)-1H-1,2,3-triazole-4-yl]methylguanosine diphosphate | about 60% inhibition at 0.4 mM | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Helicobacter pylori | - |
- |
- |
Homo sapiens | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
alpha1,3-fucosyltransferase | - |
Helicobacter pylori |
alpha1,3-fucosyltransferase IX | - |
Homo sapiens |
FucT | - |
Helicobacter pylori |
FucT IX | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0503 | - |
dGDP | at pH 4.5 and 37°C | Homo sapiens | |
0.0779 | - |
GDP | at pH 4.5 and 37°C | Homo sapiens | |
0.0807 | - |
GTP | at pH 4.5 and 37°C | Homo sapiens | |
0.102 | - |
GDP-6-amino-beta-L-fucose | at pH 4.5 and 37°C | Homo sapiens | |
0.137 | - |
[1-(beta-L-fucopyranosyl)-1H-1,2,3-triazole-4-yl]methylguanosine diphosphate | at pH 4.5 and 37°C | Homo sapiens | |
0.186 | - |
[1-(beta-D-galactopyranosyl)-1H-1,2,3-triazole-4-yl] methylguanosine diphosphate | at pH 4.5 and 37°C | Homo sapiens | |
0.19 | - |
[1-(beta-D-fucopyranosyl)-1H-1,2,3-triazole-4-yl]methylguanosine diphosphate | at pH 4.5 and 37°C | Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.049 | - |
at pH 4.5 and 37°C | Homo sapiens | dGDP | |
0.059 | - |
at pH 4.5 and 37°C | Homo sapiens | GDP | |
0.094 | - |
at pH 4.5 and 37°C | Homo sapiens | GTP | |
0.104 | - |
at pH 4.5 and 37°C | Homo sapiens | GDP-6-amino-beta-L-fucose | |
0.134 | - |
at pH 4.5 and 37°C | Homo sapiens | [1-(beta-D-fucopyranosyl)-1H-1,2,3-triazole-4-yl]methylguanosine diphosphate | |
0.139 | - |
at pH 4.5 and 37°C | Homo sapiens | [1-(beta-L-fucopyranosyl)-1H-1,2,3-triazole-4-yl]methylguanosine diphosphate | |
0.247 | - |
at pH 4.5 and 37°C | Homo sapiens | [1-(beta-D-galactopyranosyl)-1H-1,2,3-triazole-4-yl] methylguanosine diphosphate |