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Literature summary for 2.4.1.56 extracted from

  • Sun, S.; Scheffler, N.K.; Gibson, B.W.; Wang, J.; Munson, R.S., Jr.
    Identification and characterization of the N-acetylglucosamine glycosyltransferase gene of Haemophilus ducreyi (2002), Infect. Immun., 70, 5887-5892.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.1.56

Cloned(Commentary)

Cloned (Comment) Organism
lgtA gene encoding N-acetylglucosamine glycosyltransferase is cloned and expressed in Escherichia coli DH5alphapcnB, predicted amino acid sequence [Haemophilus] ducreyi
lgtA lipooligosaccharide N-acetylglucosamine glycosyltransferase gene, amino acid sequence Neisseria gonorrhoeae

Protein Variants

Protein Variants Comment Organism
additional information isogenic mutant, strain 35000HP-RSM212, with insertionally inactivated lgtA gene lacks N-acetylglucosamine and distal sugars in the lipooligosaccharide produced by the parental strain 35000HP [Haemophilus] ducreyi

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information [Haemophilus] ducreyi involved in synthesis of glycoforms of lipooligosaccharide: synthesis of the A-branch and B-branch ?
-
 ?

Organism

Organism UniProt Comment Textmining
Neisseria gonorrhoeae
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-
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[Haemophilus] ducreyi
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 strains 35000HP and 35000HP-RSM212
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information involved in synthesis of glycoforms of lipooligosaccharide: synthesis of the A-branch and B-branch [Haemophilus] ducreyi ?
-
 ?
UDP-N-acetyl-D-glucosamine + lipooligosacccharide
-
 Neisseria gonorrhoeae UDP + N-acetyl-D-glucosaminyllipooligosaccharide
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 ?
UDP-N-acetyl-D-glucosamine + lipooligosacccharide transfers N-acetylglucosamine to lipooligosaccharides, structure of the lipooligosaccharide [Haemophilus] ducreyi UDP + N-acetyl-D-glucosaminyllipooligosaccharide
-
 ?