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Literature summary for 2.4.1.41 extracted from

  • Gomes, J.; Marcos, N.T.; Berois, N.; Osinaga, E.; Magalhaes, A.; Pinto-de-Sousa, J.; Almeida, R.; Gaertner, F.; Reis, C.A.
    Expression of UDP-N-acetyl-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase-6 in gastric mucosa, intestinal metaplasia, and gastric carcinoma (2009), J. Histochem. Cytochem., 57, 79-86.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
gastric carcinoma cell expression analysis of ppGalNAc-T6 in gastric mucosa, intestinal metaplasia, and gastric carcinomas, the isozyme shows a heterogeneous expression and staining pattern Homo sapiens
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stomach expression analysis of ppGalNAc-T6 in gastric mucosa, intestinal metaplasia, and gastric carcinomas Homo sapiens
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Synonyms

Synonyms Comment Organism
ppGalNAc-T6
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Homo sapiens
UDP-N-acetyl-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase-6
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Homo sapiens

General Information

General Information Comment Organism
malfunction aberrant mucin O-glycosylation is often observed in cancer and is characterized by the expression of immature simple mucin-type carbohydrate antigens. Altered expression of ppGalNAc-Ts can be one of the mechanisms that explain the changes in mucin O-glycosylation during malignant transformation Homo sapiens
physiological function ppGalNAc-T6 is one of the enzymes responsible for the initial step in mucin O-glycosylation Homo sapiens