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Literature summary for 2.4.1.41 extracted from

  • Hatanaka, K.; Slama, J.T.; Elbein, A.D.
    Synthesis of a new inhibitor of the UDP-GalNAc:polypeptide galactosaminyl transferase (1991), Biochem. Biophys. Res. Commun., 175, 668-672.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
UMP-1-hexadecanesulfonic anhydride 50% inhibition at 0.16 mM, competitive Sus scrofa
UMP-1-octanesulfonic anhydride
-
Sus scrofa
UMP-butanesulfonic anhydride
-
Sus scrofa

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ requirement Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
submaxillary gland
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetyl-D-galactosamine + apomucin porcine apomucin Sus scrofa UDP + N-acetyl-D-galactosaminyl-apomucin
-
?
UDP-N-acetyl-D-galactosamine + polypeptide O-glycosylation of the polypeptide, acceptor: porcine stomach mucin Sus scrofa UDP + N-acetyl-D-galactosaminyl-polypeptide
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Sus scrofa