Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.1.38 extracted from

  • Ramakrishnan, B.; Shah, P.S.; Qasba, P.K.
    alpha-Lactalbumin (LA) stimulates milk beta-1,4-galactosyltransferase I (beta4Gal-T1) to transfer glucose from UDP-glucose to N-acetylglucosamine. Crystal structure of beta4Gal-T1*LA complex with UDP-Glc (2001), J. Biol. Chem., 276, 37665-37671.
    View publication on PubMed
Search for more literature for 2.4.1.38

Activating Compound

Activating Compound Comment Organism Structure
alpha-lactalbumin stimulates transfer of glucose from UDPglucose to N-acetylglucosamine Bos taurus
alpha-lactalbumin stimulates transfer of galactose from UDPgalactose to N-acetylgalactosamine Bos taurus

Crystallization (Commentary)

Crystallization (Comment) Organism
crystal structure of enzyme-alpha-lactalbumin complex with UDP-Glc Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
milk
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme also catalyzes transfer of glucose from UDPglucose to N-acetylglucosamine Bos taurus ?
-
 ?
UDPgalactose + glucose in presence of alpha-lactalbumin Bos taurus lactose + UDP
-
 ?
UDPgalactose + N-acetylglucosamine
-
 Bos taurus UDP + N-acetyllactosamine
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
additional information
-
 additional information turnover number for UDPglucose in absence of alpha-lactalbumin is 3.48 and 14.8 in presence of alpha-lactalbumin Bos taurus