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Literature summary for 2.4.1.274 extracted from

  • Tokuda, N.; Numata, S.; Li, X.; Nomura, T.; Takizawa, M.; Kondo, Y.; Yamashita, Y.; Hashimoto, N.; Kiyono, T.; Urano, T.; Furukawa, K.; Furukawa, K.
    beta4GalT6 is involved in the synthesis of lactosylceramide with less intensity than beta4GalT5 (2013), Glycobiology, 23, 1175-1183.
    View publication on PubMed
Search for more literature for 2.4.1.274

Organism

Organism UniProt Comment Textmining
Mus musculus
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Mus musculus Q9JMK0
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Source Tissue

Source Tissue Comment Organism Textmining
fibroblast isoform beta4GalT5 works predominantly in mouse embryonic fibroblasts Mus musculus
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kidney male mice show much higher activity of LacCer synthesis than female mice in the kidney. Expression levels of the B4galt5 gene correlate with the LacCer synthase activity in the kidney Mus musculus
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additional information expression levels of B4galt6 gene is almost equivalent between male and female mice Mus musculus
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Synonyms

Synonyms Comment Organism
B4GalT5
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 Mus musculus
B4GalT6
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 Mus musculus
LacCer synthase
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 Mus musculus

General Information

General Information Comment Organism
physiological function B4galt6 KO mice are born and grow up apparently normal. LacCer synthase activity and the composition of acidic glycosphingolipids in the brain are almost equivalent or minimally different between wild-type and KO mice. B4GalT6 does not act as a major beta4GalT on the modification of glycoproteins Mus musculus