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Literature summary for 2.4.1.255 extracted from

  • Hartweck, L.M.; Scott, C.L.; Olszewski, N.E.
    Two O-linked N-acetylglucosamine transferase genes of Arabidopsis thaliana L. Heynh. have overlapping functions necessary for gamete and seed development (2002), Genetics, 161, 1279-1291.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
SEC protein expressed in Escherichia coli Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
sec spy double mutant double-mutant embryos aborted at various stages of development and no double-mutant seedlings are obtained. These results indicate that OGT activity is required during gametogenesis and embryogenesis with lethality occurring when parentally derived SEC, SPY, and/or O-GlcNAcylated proteins become limiting Arabidopsis thaliana
sec-1 has a tDNA insertion within the exon encoding the ninth tetratricopeptide repeat, no obvious phenotype. Two SEC tDNA insertional mutants are identified and analyzed. sec mutant plants do not exhibit obvious phenotypes, sec and spy mutations have a synthetic lethal interaction Arabidopsis thaliana
sec-2 contains an insertion within an intron adjacent to exons encoding the putative catalytic portion of the protein, no obvious phenotype. Two SEC tDNA insertional mutants are identified and analyzed. sec mutant plants do not exhibit obvious phenotypes, sec and spy mutations have a synthetic lethal interaction Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Arabidopsis thaliana catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to Ser/Thr residues of proteins ?
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?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q9M8Y0 ecotype Columbia
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Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to Ser/Thr residues of proteins Arabidopsis thaliana ?
-
?

Synonyms

Synonyms Comment Organism
O-linked N-acetylglucosamine transferase
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Arabidopsis thaliana
OGT
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Arabidopsis thaliana
SEC
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Arabidopsis thaliana
SECRET AGENT SEC, protein is similar to animal O-linked N-acetylglucosamine transferase (OGT) Arabidopsis thaliana
spindly SPY, protein is similar to animal O-linked N-acetylglucosamine transferase (OGT) Arabidopsis thaliana
SPY
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Arabidopsis thaliana