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Literature summary for 2.4.1.255 extracted from
- Microinjection of recombinant O-GlcNAc transferase potentiates Xenopus oocytes M-phase entry (2008), Biochem. Biophys. Res. Commun., 369, 539-546.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| recombinant production of human sOGT and ncOGT in Escherichia coli | Homo sapiens |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| ncOGT | long OGT isoform, nucleocytoplasmic OGT, microinjected into immature oocytes prior to progesterone incubation | Homo sapiens |
| sOGT | N-terminally truncated isoform, short OGT, microinjected into immature oocytes prior to progesterone incubation | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | enzyme is a key molecule for the timely progression of the cell cycle. Microinject recombinant proteins into oocytes to detail the relationship between cell cycle and O-GlcNAc | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| gel filtration | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| KKKYPGGSTPVSSANMM + UDP-GlcNAc | Pep-CKII, known natural substrate for OGT | Homo sapiens | UDP + ? | - |
? | |
| additional information | enzyme is a key molecule for the timely progression of the cell cycle. Microinject recombinant proteins into oocytes to detail the relationship between cell cycle and O-GlcNAc | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| mOGT | mitochondrial OGT | Homo sapiens |
| O-GlcNAc transferase | - |
Homo sapiens |
| OGT | - |
Homo sapiens |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
assay at | Homo sapiens |
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Release 2023.1 (January 2023)
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