Literature summary for 2.4.1.212 extracted from

Miyake, Y.; Sakurai, M.; Tanaka, S.; Tunjung, W.A.; Yokoo, M.; Matsumoto, H.; Aso, H.; Yamaguchi, T.; Sato, E.
Expression of hyaluronan synthase 1 and distribution of hyaluronan during follicular atresia in pig ovaries (2009), Biol. Reprod., 80, 249-257.

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Organism

Organism	UniProt	Comment	Textmining
Sus scrofa	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
macrophage	HAS1 expression is shown in 55.7% of SIRPA-positive macrophages in stage III follicles	Sus scrofa	-
ovarian follicle	expression of isoform HAS1 in theca cells of healthy and early atretic follicles of stage I and stage II and in progressing atretic stage III follicles	Sus scrofa	-
ovary	-	Sus scrofa	-
theca cell	expression of isoform HAS1 in theca cells of healthy and early atretic follicles of stage I and stage II and in progressing atretic stage III follicles	Sus scrofa	-

Expression

Organism	Comment	Expression
Sus scrofa	during atresia, HAS1 mRNA and protein expression is markedly up-regulated inovary. HAS2 and HAS3 mRNA expression levels are low and very low to undetectable, respectively	up

General Information

General Information	Comment	Organism
physiological function	hyaluronan concentration in follicular fluids increases during atresia. Isoform HAS1 may be the dominant HAS protein in theca cells to produce hyaluronan in pig ovaries	Sus scrofa

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Release 2023.1 (January 2023)