Cloned (Comment) | Organism |
---|---|
stable expression of isozyme UGT2B7 Tyr268 variant in HEK-293 cells | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetic modeling of the interactions between 4-methylumbelliferone, 1-naphthol, and zidovudine glucuronidation by UGT2B7 provides evidence for multiple substrate binding and effector sites, multisite kinetic equilibria models and two-site inhibition model for a substrate exhibiting Michaelis-Menten kinetics, three-site model for heteroactivation, overview | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P16662 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | kinetic modeling of the interactions between 4-methylumbelliferone, 1-naphthol, and zidovudine glucuronidation by UGT2B7 provides evidence for multiple substrate binding and effector sites, overview | Homo sapiens | ? | - |
? | |
UDP-D-glucuronate + 1-naphthol | - |
Homo sapiens | UDP + 1-naphthyl beta-D-glucuronoside | - |
? | |
UDP-D-glucuronate + 4-methylumbelliferone | - |
Homo sapiens | UDP + 4-methylumbelliferonyl beta-D-glucuronoside | - |
? | |
UDP-D-glucuronate + zidovudine | - |
Homo sapiens | UDP + zidovudine beta-D-glucuronoside | - |
? |
Synonyms | Comment | Organism |
---|---|---|
UDP-glucuronosyltransferase 2B7 | - |
Homo sapiens |
UGT2B7 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Homo sapiens |