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Literature summary for 2.4.1.17 extracted from

  • Sorich, M.J.; McKinnon, R.A.; Miners, J.O.; Smith, P.A.
    The importance of local chemical structure for chemical metabolism by human uridine 5-diphosphate-glucuronosyltransferase (2006), J. Chem. Inf. Model., 46, 2692-2697.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information general chemical properties, such as chemical size, shape, flexibility, and hydrophobicity, may be of secondary importance to the steric and electronic character immediately local to the nucleophilic atom. Molecular recognition based on the local structure is likely to be important for the ability of UGT to detoxify chemicals that differ greatly in gross molecular structure Homo sapiens ?
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