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Literature summary for 2.4.1.17 extracted from

  • Barbier, O.; Belanger, A.; Hum, D.W.
    Cloning and characterization of a simian UDP-glucuronosyltransferase enzyme UGT2B20, a novel C19 steroid-conjugating protein (1999), Biochem. J., 337, 567-574.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.1.17

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0011
-
 androstane-3alpha,17beta diol apparent Km for UGT2B20 Macaca fascicularis
0.0023
-
 dihydrotestosterone apparent Km for UGT2B20 Macaca fascicularis
0.0046
-
 testosterone apparent Km for UGT2B20 Macaca fascicularis

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Macaca fascicularis
-
 cynomolgus monkey
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland
-
 Macaca fascicularis
-
breast
-
 Homo sapiens
-
epididymis
-
 Macaca fascicularis
-
kidney
-
 Homo sapiens
-
kidney
-
 Macaca fascicularis
-
liver
-
 Homo sapiens
-
liver
-
 Macaca fascicularis
-
mammary gland
-
 Homo sapiens
-
mammary gland
-
 Macaca fascicularis
-
prostate gland
-
 Homo sapiens
-
prostate gland
-
 Macaca fascicularis
-
small intestine
-
 Homo sapiens
-
small intestine
-
 Macaca fascicularis
-
testis
-
 Homo sapiens
-
vaginal epithelium
-
 Macaca fascicularis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-naphthol + UDP-glucuronate
-
 Homo sapiens naphth-1-yl-beta-D-glucuronide + UDP
-
 ?
1-naphthol + UDP-glucuronate
-
 Macaca fascicularis naphth-1-yl-beta-D-glucuronide + UDP
-
 ?
2-methoxy-4-(2-propenyl)phenol + UDPglucuronate
-
 Macaca fascicularis UDP + 2-methoxy-4-(2-propenyl)phenylglucuronide
-
 ?
4-methylumbelliferone + UDP-glucuronate
-
 Homo sapiens UDP + 4-methylumbelliferyl-7-O-beta-D-glucuronide
-
 ?
4-methylumbelliferone + UDP-glucuronate
-
 Macaca fascicularis UDP + 4-methylumbelliferyl-7-O-beta-D-glucuronide
-
 ?
4-nitrophenol + UDP-glucuronate
-
 Homo sapiens 4-nitrophenyl beta-D-glucuronide + UDP
-
 ?
4-nitrophenol + UDP-glucuronate
-
 Macaca fascicularis 4-nitrophenyl beta-D-glucuronide + UDP
-
 ?
5alpha-androstane-3alpha,17beta-diol + UDP-glucuronate
-
 Homo sapiens UDP + 5alpha-androstane-3alpha,17beta-diol O-glucuronide
-
 ?
5alpha-androstane-3alpha,17beta-diol + UDP-glucuronate
-
 Macaca fascicularis UDP + 5alpha-androstane-3alpha,17beta-diol O-glucuronide
-
 ?
5beta-androstane-3alpha,17beta-diol + UDP-glucuronate
-
 Macaca fascicularis UDP + 5beta-androstane-3alpha,17beta-diol O-glucuronide
-
 ?
androstane-3alpha,17beta diol + UDPglucuronate
-
 Macaca fascicularis UDP + androstane-3alpha,17beta diol O-glucuronide
-
 ?
scopoletin + UDPglucuronate
-
 Homo sapiens UDP + scopoletin O-glucuronide
-
 ?
scopoletin + UDPglucuronate
-
 Macaca fascicularis UDP + scopoletin O-glucuronide
-
 ?
testosterone + UDPglucuronate
-
 Macaca fascicularis UDP + testosterone O-glucuronide
-
 ?
troglitazone + UDPglucuronate
-
 Homo sapiens UDP + troglitazone 6-O-glucuronide
-
 ?
UDP-alpha-D-glucuronate + biphenyl-4,4'-diol
-
 Macaca fascicularis UDP + 4'-hydroxybiphenyl-4-yl beta-D-glucopyranosiduronate
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
35
-
-
 Macaca fascicularis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
 Macaca fascicularis