Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.1.17 extracted from

  • Yokota, H.; Ohgiya, N.; Ishihara, G.; Ohta, K.; Yuasa, A.
    Purification and properties of UDP-glucuronyltransferase from kidney microsomes of beta-naphthoflavone-treated rat (1989), J. Biochem., 106, 248-252.
    View publication on PubMed
Search for more literature for 2.4.1.17

Activating Compound

Activating Compound Comment Organism Structure
cholate activation Rattus norvegicus
phosphatidylcholine required by purified preparations for optimal activity Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 Wistar strain
-
Rattus norvegicus Wistar
-
 Wistar strain
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein mannose-type oligosaccharide chains Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-naphthol + UDP-glucuronate
-
 Rattus norvegicus naphth-1-yl-beta-D-glucuronide + UDP
-
 ?
1-naphthol + UDP-glucuronate
-
 Rattus norvegicus Wistar naphth-1-yl-beta-D-glucuronide + UDP
-
 ?
4-hydroxybiphenyl + UDP-glucuronate very low activity Rattus norvegicus UDP + 4-hydroxybiphenyl 4-O-beta-D-glucuronide
-
 ?
4-hydroxybiphenyl + UDP-glucuronate very low activity Rattus norvegicus Wistar UDP + 4-hydroxybiphenyl 4-O-beta-D-glucuronide
-
 ?
4-methylumbelliferone + UDP-glucuronate
-
 Rattus norvegicus UDP + 4-methylumbelliferyl-7-O-beta-D-glucuronide
-
 ?
4-methylumbelliferone + UDP-glucuronate
-
 Rattus norvegicus Wistar UDP + 4-methylumbelliferyl-7-O-beta-D-glucuronide
-
 ?
4-nitrophenol + UDP-glucuronate
-
 Rattus norvegicus 4-nitrophenyl beta-D-glucuronide + UDP
-
 ?
4-nitrophenol + UDP-glucuronate
-
 Rattus norvegicus Wistar 4-nitrophenyl beta-D-glucuronide + UDP
-
 ?
bilirubin + UDPglucuronate very low activity Rattus norvegicus bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP
-
 ?
bilirubin + UDPglucuronate very low activity Rattus norvegicus Wistar bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP
-
 ?
UDP-alpha-D-glucuronate + chloramphenicol very low activity Rattus norvegicus UDP + chloramphenicol beta-D-glucuronide
-
 ?

Subunits

Subunits Comment Organism
? isozymes GT-1 and GT-2, identical subunit weights, but different N-terminal amino acid sequences Rattus norvegicus
? all values determined by SDS-PAGE Rattus norvegicus
? deglycosylated isozymes GT-1 and GT-2 Rattus norvegicus