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Literature summary for 2.4.1.15 extracted from

  • Hespeels, B.; Li, X.; Flot, J.F.; Pigneur, L.M.; Malaisse, J.; Da Silva, C.; Van Doninck, K.
    Against all odds: trehalose-6-phosphate synthase and trehalase genes in the bdelloid rotifer Adineta vaga were acquired by horizontal gene transfer and are upregulated during desiccation (2015), PLoS ONE, 10, e0131313.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene tps, four copies, DNA and amino acid sequence determination and analysis, phylogenetic analysis and tree, quantitative reverse transcriptase PCR enzyme expression analysis and profile Adineta vaga

Organism

Organism UniProt Comment Textmining
Adineta vaga
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gene TPS
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Source Tissue

Source Tissue Comment Organism Textmining
additional information bdelloids show low tps gene expression levels, but strong overexpression of the TPS genes is observed when bdelloids enter desiccation. Quantitative expression analysis Adineta vaga
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Synonyms

Synonyms Comment Organism
TPS
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Adineta vaga
trehalose-6-phosphate synthase
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Adineta vaga

General Information

General Information Comment Organism
evolution Adineta vaga likely has acquired its trehalose biosynthesis and hydrolysis genes by horizontal gene transfers. The four trehalose-6-phosphate synthase TPS copies of Adineta vaga appear more closely related to plant and fungi proteins, as well as to some protists, whereas the seven TRE copies of the gene encoding trehalase fall in bacterial clades Adineta vaga
physiological function possible signaling role of trehalose-6-phosphate or trehalose in the dessication process, sugars are proposed to play a role in osmotic adjustment, to stabilize biomolecules and membranes, and to act as a replacement for water Adineta vaga