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Literature summary for 2.4.1.147 extracted from

  • An, G.; Wei, B.; Xia, B.; McDaniel, J.M.; Ju, T.; Cummings, R.D.; Braun, J.; Xia, L.
    Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans (2007), J. Exp. Med., 204, 1417-1429.
    View publication on PubMedView publication on EuropePMC
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Protein Variants

Protein Variants Comment Organism
additional information C3GnT-deficient mice display a discrete, colonspecific reduction in Muc2 protein and increased permeability of the intestinal barrier. These mice are highly susceptible to experimental triggers of colitis and colorectal adenocarcinoma Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus C3GnT-deficient mice display a discrete, colonspecific reduction in Muc2 protein and increased permeability of the intestinal barrier. These mice are highly susceptible to experimental triggers of colitis and colorectal adenocarcinoma ?
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Organism

Organism UniProt Comment Textmining
Mus musculus
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information C3GnT-deficient mice display a discrete, colonspecific reduction in Muc2 protein and increased permeability of the intestinal barrier. These mice are highly susceptible to experimental triggers of colitis and colorectal adenocarcinoma Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
C3GnT
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 Mus musculus
core 3 beta 1,3-N-acetylglucosaminyltransferase
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 Mus musculus