Application | Comment | Organism |
---|---|---|
medicine | the enzyme would be a useful marker for distinguishing between benign adenomas and premalignant lesions | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
Golgi apparatus | in normal stomach and colon the enzyme is strongly expressed in the Golgi region of the epithelium | Homo sapiens | 5794 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | expression of the enzyme is closely regulated during differentiation and dedifferentiation. Rge expression of the enzyme dramatically decreased in cancerous tissues, and the changes to the core structures of O-glycans give rise to phenotypic changes of cancer cells, such as mobility and metastatic activity | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Caco-2 cell | expression of the enzyme is markedly down-regulated in gastric and colorectal carcinomas | Homo sapiens | - |
colon | in normal stomach and colon the enzyme is strongly expressed in the Golgi region of the epithelium | Homo sapiens | - |
stomach | in normal stomach and colon the enzyme is strongly expressed in the Golgi region of the epithelium | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | expression of the enzyme is closely regulated during differentiation and dedifferentiation. Rge expression of the enzyme dramatically decreased in cancerous tissues, and the changes to the core structures of O-glycans give rise to phenotypic changes of cancer cells, such as mobility and metastatic activity | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
beta3Gn-T6 | - |
Homo sapiens |
core 3 synthase | - |
Homo sapiens |