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Literature summary for 2.4.1.144 extracted from

  • Xu, Q.; Akama, R.; Isaji, T.; Lu, Y.; Hashimoto, H.; Kariya, Y.; Fukuda, T.; Du, Y.; Gu, J.
    Wnt/beta-catenin signaling down-regulates N-acetylglucosaminyltransferase III expression: the implications of two mutually exclusive pathways for regulation (2011), J. Biol. Chem., 286, 4310-4318.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.1.144

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
DLD-1/alpha-cat cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetyl-D-glucosamine + GlcNAcbeta(1->2)Manalpha(1->6)(GlcNAcbeta(1->2)Manbeta(1->3)Manbeta(1->4)GlcNAcbeta(1->4)GlcNAc-NH(CH2)4NH(2-pyridyl)
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
GnT-III
-
 Homo sapiens
N-acetylglucosaminyltransferase III
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens stimulation of the Wnt signaling pathway by the addition of exogenous Wnt3a or SB415286 consistently and significantly inhibits enzyme expression down
Homo sapiens shRNA knockdown of beta-catenin results in a dramatic increase in enzyme expression up