Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
Golgi apparatus | - |
Rattus norvegicus | 5794 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-galactose + O-beta-D-xylosylprotein | Rattus norvegicus | - |
UDP + 4-beta-D-galactosyl-O-beta-D-xylosylprotein | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Sprague-Dawley rat | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
astrocyte | in the lesion site after spinal cord injury | Rattus norvegicus | - |
inflammatory cell | - |
Rattus norvegicus | - |
macrophage | in the lesion site after spinal cord injury | Rattus norvegicus | - |
microglia | OX-42-positive microglia in the lesion site after spinal cord injury | Rattus norvegicus | - |
neutrophil | in the lesion site after spinal cord injury | Rattus norvegicus | - |
oligodendrocyte | in the lesion site after spinal cord injury | Rattus norvegicus | - |
spinal cord | in the lesion site after spinal cord injury | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-galactose + O-beta-D-xylosylprotein | - |
Rattus norvegicus | UDP + 4-beta-D-galactosyl-O-beta-D-xylosylprotein | - |
? |
Synonyms | Comment | Organism |
---|---|---|
beta-1,4-galactosyltransferase I | - |
Rattus norvegicus |
beta-1,4-GalT-I | - |
Rattus norvegicus |
Organism | Comment | Expression |
---|---|---|
Rattus norvegicus | in injured spinal cords, enzyme is significantly increased after 8 h, beta-1,4-GalT-I mRNA reaches the peak at 1 day after spinal cord contusion, then gradually reduced from day 5 to day 7, recovers to the baseline level at 14 day | up |
General Information | Comment | Organism |
---|---|---|
physiological function | beta-1,4-galactosyltransferase I is a key inflammatory mediator that plays a critical role in the initiation and maintenance of inflammatory reaction in diseases, beta-1,4-GalT-I is associated with E-selectin during the pathological process of secondary response after Spinal cord injury | Rattus norvegicus |