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Literature summary for 2.4.1.11 extracted from

  • Freitas, F.Z.; de Paula, R.M.; Barbosa, L.C.; Terenzi, H.F.; Bertolini, M.C.
    cAMP signaling pathway controls glycogen metabolism in Neurospora crassa by regulating the glycogen synthase gene expression and phosphorylation (2010), Fungal Genet. Biol., 47, 43-52.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Neurospora crassa
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-
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Synonyms

Synonyms Comment Organism
GSN
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Neurospora crassa

Expression

Organism Comment Expression
Neurospora crassa heat-shock down-regulates gsn gene transcription in wild-type as well as in mutants deficient in adenylyl cyclase activity and a temperature-sensitive mutant defective in the regulatory subunit of protein kinase A down

General Information

General Information Comment Organism
physiological function a mutant strain defective in adenylyl cyclase activity accumulates, during vegetative growth, glycogen levels much higher than the wild type strain. The gsn transcript is not increased in this strain but the GSN protein is less phosphorylated in vitro, and therefore more active Neurospora crassa