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Literature summary for 2.4.1.109 extracted from

  • Immervoll, T.; Gentzsch, M.; Tanner, W.
    PMT3 and PMT4, two new members of the protein-O-mannosyltransferase gene family of Saccharomyces cerevisiae (1995), Yeast, 11, 1345-1351.
    View publication on PubMed
Search for more literature for 2.4.1.109

Cloned(Commentary)

Cloned (Comment) Organism
-
 Saccharomyces cerevisiae
DNA sequence determination Saccharomyces cerevisiae

Protein Variants

Protein Variants Comment Organism
additional information homozygous diploid double disruption mutants of PMT1 and PMT2 lead to reduced enzyme activity and a severe defect in sporulation, lethal phenotype when combined with a disruption mutation in dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase, EC 2.4.1.130, genes Saccharomyces cerevisiae
additional information PMT3 and 4 gene disruption does not alter enzyme activity Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Saccharomyces cerevisiae 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dolichyl phosphate D-mannose + protein Saccharomyces cerevisiae production of cell-wall mannoproteins dolichyl phosphate + O-D-mannosylprotein
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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 gene PMT1
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Saccharomyces cerevisiae
-
 gene PMT2
-
Saccharomyces cerevisiae P46971 gene PMT4
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Saccharomyces cerevisiae P47190 gene PMT3
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dolichyl phosphate D-mannose + protein
-
 Saccharomyces cerevisiae dolichyl phosphate + O-D-mannosylprotein
-
 ?
dolichyl phosphate D-mannose + protein the enzyme transfers mannosyl residues to the hydroxyl of serine or threonine residues Saccharomyces cerevisiae dolichyl phosphate + O-D-mannosylprotein
-
 ?
dolichyl phosphate D-mannose + protein production of cell-wall mannoproteins Saccharomyces cerevisiae dolichyl phosphate + O-D-mannosylprotein
-
 ?
additional information
-
 Saccharomyces cerevisiae ?
-
 ?
additional information PMT3 behaves as a dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase, EC 2.4.1.130 Saccharomyces cerevisiae ?
-
 ?

Synonyms

Synonyms Comment Organism
More
-
 Saccharomyces cerevisiae
More PMT3 behaves as a dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase, EC 2.4.1.130 Saccharomyces cerevisiae
PMT
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 Saccharomyces cerevisiae
protein mannosyltransferase
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 Saccharomyces cerevisiae