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Literature summary for 2.4.1.101 extracted from

  • Reck, F.; Springer, M.; Meinjohanns, E.; Paulsen, H.; Brockhausen, I.; Schachter, H.
    Synthetic substrate analogs for UDP-GlcNAc: manalpha1-3R beta1-2-N-acetylglucosaminyltransferase I. Substrate specificity and inhibitors for the enzyme (1995), Glycoconj. J., 12, 747-754.
    View publication on PubMed
Search for more literature for 2.4.1.101

Inhibitors

Inhibitors Comment Organism Structure
additional information several inhibitory synthetic acceptor substrate analogues, overview; strategies for inhibitor design based on substrate specificities of the enzyme Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information Km-values for several synthetic acceptor substrate analogues, overview Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
20
-
 purified enzyme Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information specificity for several synthetic acceptor substrate analogues, overview Rattus norvegicus ?
-
 ?
UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(alpha-D-mannosyl-1,3)-alpha-D-mannosyl-1,6-(alpha-D-mannosyl-1,3)-beta-D-mannosyl-1,4-N-acetyl-D-glucosaminyl-R R: 1,4-N-acetyl-D-glucosaminyl-Asn Rattus norvegicus UDP + alpha-D-mannosyl-1,6-(alpha-D-mannosyl-1,3)-alpha-D-mannosyl-1,6-(N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-1,4-N-acetyl-D-glucosaminyl-R R: 1,4-N-acetyl-D-glucosaminyl-1,4-N-acetyl-D-glucosaminyl-Asn ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
additional information
-
 additional information several inhibitory synthetic acceptor substrate analogues, overview Rattus norvegicus