Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.1.1 extracted from

  • Buschiazzo, A.; Ugalde, J.E.; Guerin, M.E.; Shepard, W.; Ugalde, R.A.; Alzari, P.M.
    Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation (2004), EMBO J., 23, 3196-3205.
    View publication on PubMedView publication on EuropePMC

Metals/Ions

Metals/Ions Comment Organism Structure
additional information no metal binding Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(1,4-alpha-D-glucosyl)n + phosphate Oryctolagus cuniculus polysaccharide substrate is glycogen, first step in glycogen breakdown removing one glucose at a time (1,4-alpha-D-glucosyl)n-1 + alpha-D-glucose 1-phosphate
-
r

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
muscle
-
Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(1,4-alpha-D-glucosyl)n + phosphate polysaccharide substrate is glycogen, first step in glycogen breakdown removing one glucose at a time Oryctolagus cuniculus (1,4-alpha-D-glucosyl)n-1 + alpha-D-glucose 1-phosphate
-
r
(1,4-alpha-D-glucosyl)n + phosphate polysaccharide substrate is glycogen, phosphorolysis is the preferred reaction Oryctolagus cuniculus (1,4-alpha-D-glucosyl)n-1 + alpha-D-glucose 1-phosphate
-
r

Subunits

Subunits Comment Organism
More enzyme has 2 distinct Rossmann domains separated by a large cleft that permits important flexibility, crystal structure, 1A8I, comparison with the glycogen synthase and amino acid sequence alignment Oryctolagus cuniculus

Synonyms

Synonyms Comment Organism
glycogen phosphorylase
-
Oryctolagus cuniculus
GP
-
Oryctolagus cuniculus
More enzyme belongs to the GT-B-fold glycosyltransferase superfamily Oryctolagus cuniculus