Cloned (Comment) | Organism |
---|---|
genome sequencing, prpDBC gene cluster, prpC2 gene for 2-methylcitrate synthase, cloned into vector pTrc99a and expressed in Escherichia coli | Corynebacterium glutamicum |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
42570 | - |
prpC1, amino acid sequence calculated from cDNA | Corynebacterium glutamicum |
42600 | - |
prpC2, amino acid sequence calculated from cDNA | Corynebacterium glutamicum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
propanoyl-CoA + H2O + oxaloacetate | Aspergillus nidulans | - |
2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | Corynebacterium glutamicum | - |
2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | Escherichia coli | - |
2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | Cupriavidus metallidurans | - |
2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | Salmonella enterica | - |
2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | Escherichia coli | first key enzyme of the methylcitric acid cycle | 2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | Pseudomonas aeruginosa | first key enzyme of the methylcitric acid cycle | 2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | Yarrowia lipolytica | first key enzyme of the methylcitric acid cycle | 2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | Corynebacterium glutamicum | first key enzyme of the methylcitric acid cycle | 2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | Paraburkholderia sacchari | first key enzyme of the methylcitric acid cycle | 2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | Cupriavidus metallidurans | first key enzyme of the methylcitric acid cycle | 2-methylcitrate + CoA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus nidulans | - |
- |
- |
Corynebacterium glutamicum | - |
ATCC 13032 | - |
Corynebacterium glutamicum | Q8NSH7 | ATCC 13032, prp gene cluster | - |
Corynebacterium glutamicum | Q8NSL1 | ATCC 13032, prp gene cluster | - |
Cupriavidus metallidurans | - |
- |
- |
Cupriavidus metallidurans | Q937N9 | formerly Ralstonia eutropha, HF39 prp gene cluster | - |
Cupriavidus metallidurans | Q937N9 | formerly Ralstonia eutropha, prp gene cluster | - |
Escherichia coli | - |
- |
- |
Escherichia coli | P31660 | prp gene cluster | - |
Paraburkholderia sacchari | - |
- |
- |
Pseudomonas aeruginosa | - |
- |
- |
Salmonella enterica | Q56063 | serovar Typhimurium, prp gene cluster | - |
Yarrowia lipolytica | - |
formerly Candida lipolytica | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
propanoyl-CoA + H2O + oxaloacetate | - |
Escherichia coli | 2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | - |
Aspergillus nidulans | 2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | - |
Pseudomonas aeruginosa | 2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | - |
Yarrowia lipolytica | 2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | - |
Corynebacterium glutamicum | 2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | - |
Paraburkholderia sacchari | 2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | - |
Cupriavidus metallidurans | 2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | - |
Salmonella enterica | 2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | first key enzyme of the methylcitric acid cycle | Escherichia coli | 2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | first key enzyme of the methylcitric acid cycle | Pseudomonas aeruginosa | 2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | first key enzyme of the methylcitric acid cycle | Yarrowia lipolytica | 2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | first key enzyme of the methylcitric acid cycle | Corynebacterium glutamicum | 2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | first key enzyme of the methylcitric acid cycle | Paraburkholderia sacchari | 2-methylcitrate + CoA | - |
? | |
propanoyl-CoA + H2O + oxaloacetate | first key enzyme of the methylcitric acid cycle | Cupriavidus metallidurans | 2-methylcitrate + CoA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PrpC | - |
Corynebacterium glutamicum |