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Literature summary for 2.3.3.5 extracted from

  • Braemer, C.O.; Steinbuechel, A.
    The methylcitric acid pathway in Ralstonia eutropha: new genes identified involved in propionate metabolism (2001), Microbiology, 147, 2203-2214.
    View publication on PubMed
Search for more literature for 2.3.3.5

Application

Application Comment Organism
agriculture implications for propionate as an antifungal agent Aspergillus nidulans

Cloned(Commentary)

Cloned (Comment) Organism
prpC encoded enzyme complements a prpC mutant of Salmonella enterica serovar Typhimurium, transduction of genomic DNA ligated into the cosmid pHC79 to Escherichia coli S17-1 Cupriavidus metallidurans

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
42720
-
 amino acid sequence Cupriavidus metallidurans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
propanoyl-CoA + H2O + oxaloacetate Aspergillus nidulans
-
 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate Pseudomonas putida
-
 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate Neisseria meningitidis
-
 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate Vibrio cholerae serotype O1
-
 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate Escherichia coli first key enzyme of the methylcitric acid cycle 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate Pseudomonas aeruginosa first key enzyme of the methylcitric acid cycle 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate Salmonella enterica first key enzyme of the methylcitric acid cycle 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate Cupriavidus metallidurans first key enzyme of the methylcitric acid cycle 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate Pseudomonas putida KT 2240
-
 2-methylcitrate + CoA
-
 ?

Organism

Organism UniProt Comment Textmining
Aspergillus nidulans
-
-
-
Cupriavidus metallidurans
-
 Ralstonia eutropha CH34
-
Cupriavidus metallidurans
-
 formerly Ralstonia eutropha, HF39
-
Escherichia coli
-
-
-
Neisseria meningitidis
-
-
-
Pseudomonas aeruginosa
-
-
-
Pseudomonas putida
-
 KT2440
-
Pseudomonas putida KT 2240
-
 KT2440
-
Salmonella enterica
-
 serovar typhimurium LT2
-
Vibrio cholerae serotype O1
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
propanoyl-CoA + H2O + oxaloacetate
-
 Escherichia coli 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate
-
 Aspergillus nidulans 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate
-
 Pseudomonas aeruginosa 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate
-
 Pseudomonas putida 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate
-
 Neisseria meningitidis 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate
-
 Salmonella enterica 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate
-
 Vibrio cholerae serotype O1 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate
-
 Cupriavidus metallidurans 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate first key enzyme of the methylcitric acid cycle Escherichia coli 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate first key enzyme of the methylcitric acid cycle Pseudomonas aeruginosa 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate first key enzyme of the methylcitric acid cycle Salmonella enterica 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate first key enzyme of the methylcitric acid cycle Cupriavidus metallidurans 2-methylcitrate + CoA
-
 ?
propanoyl-CoA + H2O + oxaloacetate
-
 Pseudomonas putida KT 2240 2-methylcitrate + CoA
-
 ?