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Literature summary for 2.3.3.2 extracted from
- A metabolic variation in Penicillium spiculisporum Lehman (1968), Acta Chem. Scand., 22, 2617-2623.
General Stability
| General Stability | Organism |
|---|---|
| thiols such as mercaptoethanol or cysteine stabilize | Talaromyces trachyspermus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| lauroyl-CoA | strong substrate inhibition, does not follow Michaelis-Menten kinetics | Talaromyces trachyspermus |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.2 | - |
oxaloacetate | - |
Talaromyces trachyspermus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Talaromyces trachyspermus | - |
- |
- |
| Talaromyces trachyspermus Lehman | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Talaromyces trachyspermus |
Storage Stability
| Storage Stability | Organism |
|---|---|
| 0°C, enzyme concentration 2 mg/ml, 80 h, 50% activity | Talaromyces trachyspermus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl-CoA + H2O + oxaloacetate | - |
Talaromyces trachyspermus | citrate + CoA | - |
? | |
| butanoyl-CoA + H2O + oxaloacetate | - |
Talaromyces trachyspermus | (2S,3S)-2-hydroxyhexane-1,2,3-tricarboxylate + CoA | - |
? | |
| decanoyl-CoA + H2O + oxaloacetate | - |
Talaromyces trachyspermus | (2S,3S)-2-hydroxydodecane-1,2,3-tricarboxylate + CoA | - |
? | |
| decanoyl-CoA + H2O + oxaloacetate | - |
Talaromyces trachyspermus Lehman | (2S,3S)-2-hydroxydodecane-1,2,3-tricarboxylate + CoA | - |
? | |
| lauroyl-CoA + H2O + 2-oxoglutarate | - |
Talaromyces trachyspermus | ? | - |
? | |
| lauroyl-CoA + H2O + 2-oxoglutarate | - |
Talaromyces trachyspermus Lehman | ? | - |
? | |
| lauroyl-CoA + H2O + oxaloacetate | - |
Talaromyces trachyspermus | (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate + CoA | - |
? | |
| lauroyl-CoA + H2O + oxaloacetate | - |
Talaromyces trachyspermus Lehman | (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate + CoA | - |
? | |
| lauroyl-CoA + H2O + pyruvate | - |
Talaromyces trachyspermus | ? | - |
? | |
| lauroyl-CoA + H2O + pyruvate | - |
Talaromyces trachyspermus Lehman | ? | - |
? | |
| myristoyl-CoA + H2O + oxaloacetate | - |
Talaromyces trachyspermus | (2S,3S)-2-hydroxypentadecane-1,2,3-tricarboxylate + CoA | - |
? | |
| octanoyl-CoA + H2O + oxaloacetate | - |
Talaromyces trachyspermus | (2S,3S)-2-hydroxydecane-1,2,3-tricarboxylate + CoA | - |
? | |
| octanoyl-CoA + H2O + oxaloacetate | - |
Talaromyces trachyspermus Lehman | (2S,3S)-2-hydroxydecane-1,2,3-tricarboxylate + CoA | - |
? | |
| palmitoyl-CoA + H2O + oxaloacetate | - |
Talaromyces trachyspermus | (2S,3S)-2-hydroxyheptadecane-1,2,3-tricarboxylate + CoA | - |
? | |
| phenylacetyl-CoA + H2O + oxaloacetate | - |
Talaromyces trachyspermus | phenylcitrate + CoA | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | 35 | - |
Talaromyces trachyspermus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9 | - |
above this pH | Talaromyces trachyspermus |
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Release 2023.1 (January 2023)
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