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Literature summary for 2.3.2.5 extracted from
- Pyroglutamate-amyloid-beta and glutaminyl cyclase are colocalized with amyloid-beta in secretory vesicles and undergo activity-dependent, regulated secretion (2014), Neurodegener. Dis., 14, 85-97.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| secretory vesicle | - |
Homo sapiens | 99503 | - |
| secretory vesicle | - |
Bos taurus | 99503 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 48000 | - |
x * 48000, SDS-PAGE | Homo sapiens |
| 48000 | - |
x * 48000, SDS-PAGE | Bos taurus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| adrenal medulla | - |
Bos taurus | - |
| IMR-32 cell | - |
Homo sapiens | - |
| neuroblastoma cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-glutaminyl-amyloid beta peptide | - |
Homo sapiens | 5-oxoprolyl-amyloid beta peptide + NH3 | - |
? |  |
| L-glutaminyl-amyloid beta peptide | - |
Bos taurus | 5-oxoprolyl-amyloid beta peptide + NH3 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 48000, SDS-PAGE | Homo sapiens |
| ? | x * 48000, SDS-PAGE | Bos taurus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glutaminyl cyclase | - |
Homo sapiens |
| glutaminyl cyclase | - |
Bos taurus |
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Release 2023.1 (January 2023)
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