Application | Comment | Organism |
---|---|---|
drug development | QCT would be suitable for enzyme therapy in gluten intolerance and appear to have synergistic action with porcine intestinal extracts, potential for enzyme therapy in coeliac disease | Carica papaya |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
30000 | - |
fraction are estimated from plots of Kav against molecular weight using dextran blue, human gamma-globulin, bovine serum albumin and trypsin inhibitor as standards, mass spectrometric analysis of trypsin-digested fractions from chromatography is carried out by liquid chromatography/electrospray quadrupole time-of-flight mass spectrometry | Carica papaya |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Carica papaya | - |
- |
- |
Carica papaya | O81226 | - |
- |
Purification (Comment) | Organism |
---|---|
enzyme is semi-purified from latex crude extracts by ion exchange chromatography on a CM Sephadex column C-50 and gel filtration | Carica papaya |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
latex | - |
Carica papaya | - |
latex | estimated as a fraction of papaya latex | Carica papaya | - |
Synonyms | Comment | Organism |
---|---|---|
glutamine cyclotransferase | - |
Carica papaya |
QCT | - |
Carica papaya |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
85 | - |
heat stability of QCT up to 85°C | Carica papaya |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.5 | - |
enzyme is dissolved in phosphate buffer and used with a suspension of lysosomes in 0.154 mol/L NaCl | Carica papaya |