Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
hanging-drop vapor diffusion | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-Benzylimidazole | 0.14 mM, 58% inhibition | Homo sapiens | |
3,5-diamino-1,2-S4-triazole | 0.14 mM, 10% inhibition | Homo sapiens | |
3-Amino-1,2,4-triazole | 0.14 mM, 15% inhibition | Homo sapiens | |
4-phenyl-1,2,4-triazoleine-3,5-dione | 0.14 mM, 22% inhibition | Homo sapiens | |
5-(methylthio)-1-H-tetrazole | 0.14 mM, 11% inhibition | Homo sapiens | |
ethyl-1H-tetrazole-4-acetate | 0.14 mM, 9% inhibition | Homo sapiens | |
N-omega-acetylhistamine | 0.14 mM, 33% inhibition | Homo sapiens | |
nitron | 0.14 mM, 39% inhibition | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.6 | - |
Gln-Gln | - |
Homo sapiens | |
4.1 | - |
Gln-tert-butyl ester | - |
Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zinc | contains one zinc ion per protein molecule | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
37520 | - |
mass spectrometry analysis | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bone marrow | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gln-Gln | - |
Homo sapiens | pyroglutamyl-Gln + NH3 | - |
? | |
Gln-His-Pro | - |
Homo sapiens | pyroglutamyl-His-Pro | - |
? | |
Gln-tert-butyl ester | - |
Homo sapiens | pyroglutamyl-tert-butyl ester + NH3 | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
8.6 | - |
Gln-Gln | - |
Homo sapiens | |
20.9 | - |
Gln-tert-butyl ester | - |
Homo sapiens |