Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.2.2 extracted from

  • Ohta, H.; Sawabu, N.; Kawakami, H.; Watanabe, H.; Ozaki, K.; Toya, D.; Hattori, N.
    Characterization of g-glutamyltranspeptidase from human hepatocellular carcinoma, compared with enzymes from normal liver and cirrhotic liver (1993), Clin. Chim. Acta, 214, 83-92.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
6 isoforms in hepatic cellular carcinoma
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein sialoglycoprotein Homo sapiens
glycoprotein binding of concanavalin A Homo sapiens
glycoprotein binding of lentil lectin Homo sapiens

Purification (Commentary)

Purification (Comment) Organism
from normal and cirrhotic liver and 6 isoforms from serum of patients with cellular hepatic carcinoma Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
blood 6 isoforms, serum of patients with cellular hepatic carcinoma Homo sapiens
-
liver normal and cirrhotic liver Homo sapiens
-
liver hepatocellular carcinoma Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
25.6
-
purified enzyme, normal and cirrhotic liver Homo sapiens
102.8
-
purified enzyme of cellular hepatic carcinoma Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(5-L-glutamyl)-peptide + acceptor + H+
-
Homo sapiens peptide + 5-L-glutamyl amino acid
-
?
5-L-glutamyl-4-nitroanilide + glycylglycine
-
Homo sapiens 4-nitroaniline + 5-L-glutamylglycylglycine
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
additional information
-
pI: 4.2, liver enzyme Homo sapiens
additional information
-
pIs of 6 isoforms in hepatic cellular carcinoma Homo sapiens