Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Maleate | 1.6fold | Ovis aries | |
additional information | no effect by phthalate, pyruvate and fumarate | Ovis aries |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5,5'-dithiobis(2-nitrobenzoate) | - |
Ovis aries | |
Ca2+ | no inhibition | Ovis aries | |
Co2+ | not affected | Ovis aries | |
EDTA | weak | Ovis aries | |
iodoacetamide | - |
Ovis aries | |
iodoacetate | weak | Ovis aries | |
Mg2+ | no inhibition | Ovis aries | |
additional information | not affected by Ni2+, K+, phtalate, pyruvate and fumarate | Ovis aries | |
N-ethylmaleimide | - |
Ovis aries | |
Na+ | not affected | Ovis aries | |
p-chloromercuribenzoate | - |
Ovis aries |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetic study | Ovis aries | |
2.9 | - |
L-alpha-methyl-5-glutamyl-L-alpha-aminobutyrate | hydrolase reaction | Ovis aries |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | no effect | Ovis aries | |
K+ | no effect | Ovis aries | |
Mg2+ | no effect | Ovis aries | |
additional information | not affected by Co2+ and Ni2+ | Ovis aries | |
Na+ | no effect | Ovis aries |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ovis aries | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
a (5-L-glutamyl)-peptide + an amino acid = a peptide + a 5-L-glutamyl amino acid | mechanism | Ovis aries | |
a (5-L-glutamyl)-peptide + an amino acid = a peptide + a 5-L-glutamyl amino acid | kinetic study | Ovis aries |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Ovis aries | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(5-L-glutamyl)-peptide + acceptor + H+ | acceptor specificity, overview | Ovis aries | peptide + 5-L-glutamyl amino acid | - |
? | |
5-L-glutamyl-4-nitroanilide + H2O | hydrolase reaction | Ovis aries | 4-nitroaniline + L-glutamate | - |
ir | |
glutathione + glutathione | autotranspeptidation | Ovis aries | L-cysteinylglycine + 5-glutamyl-glutathione | - |
? | |
glutathione + H2O | hydrolase reaction, concurrent to (auto-)transpeptidation | Ovis aries | L-cysteinylglycine + L-glutamate | - |
? | |
L-alpha-methyl-5-glutamyl-L-alpha-aminobutyrate + acceptor | acceptor specificity, overview | Ovis aries | L-alpha-methyl-5-glutamyl acceptor + L-2-aminobutyrate | - |
? | |
L-alpha-methyl-5-glutamyl-L-alpha-aminobutyrate + acceptor | hydrolysis in the absence of acceptor, methyl group at alpha-C prevents autotranspeptidation | Ovis aries | L-alpha-methyl-5-glutamyl acceptor + L-2-aminobutyrate | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Ovis aries |