Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.2.2 extracted from

  • Ding, J.L.; Smith, G.D.; Peters, T.J.
    The purification of gamma-glutamyltransferase from normal rat liver (1980), Biochem. Soc. Trans., 8, 77.
    View publication on PubMed
Search for more literature for 2.3.2.2

Inhibitors

Inhibitors Comment Organism Structure
EDTA no inhibition Rattus norvegicus
Mg2+ no inhibition Rattus norvegicus
p-chloromercuribenzoate weak Rattus norvegicus
Zn2+ 95% inhibition at 5 mM; reversible by EDTA; strong Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.41
-
 5-L-glutamyl-7-amido-4-methylcoumarin
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Rattus norvegicus 16020
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 Wistar
-
Rattus norvegicus Wistar
-
 Wistar
-

Purification (Commentary)

Purification (Comment) Organism
Lubrol WX/deoxycholate Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(5-L-glutamyl)-peptide + acceptor + H+
-
 Rattus norvegicus peptide + 5-L-glutamyl amino acid
-
 ?
(5-L-glutamyl)-peptide + acceptor + H+
-
 Rattus norvegicus Wistar peptide + 5-L-glutamyl amino acid
-
 ?
5-L-glutamyl-7-amido-4-methylcoumarin + glycylglycine
-
 Rattus norvegicus 7-amino-4-methylcoumarin + 5-L-glutamyl-glycylglycine
-
 ?
5-L-glutamyl-7-amido-4-methylcoumarin + glycylglycine
-
 Rattus norvegicus Wistar 7-amino-4-methylcoumarin + 5-L-glutamyl-glycylglycine
-
 ?