Cloned (Comment) | Organism |
---|---|
gene AANAT2, DNA and amino acid sequence determination and analysis, developmental expression analysis by quantitative real time PCR analysis, phylogenetic analysis, overview | Solea senegalensis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + serotonin | Solea senegalensis | first step in melatonin biosynthesis | CoA + N-acetylserotonin | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Solea senegalensis | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
larva | isozyme AANAT2 developmental expression pattern, overview | Solea senegalensis | - |
pineal gland | pineal gland-specific isozyme AANAT2 is specifically expressed in pineal opsin-immunoreactive photoreceptor cells, developmental expression pattern, s significant 60fold reduction in Aanat2 expression occurs just before metamorphosis, overview | Solea senegalensis | - |
retina | retina-specific isozyme AANAT1 | Solea senegalensis | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + serotonin | - |
Solea senegalensis | CoA + N-acetylserotonin | - |
? | |
acetyl-CoA + serotonin | first step in melatonin biosynthesis | Solea senegalensis | CoA + N-acetylserotonin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AANAT | - |
Solea senegalensis |
arylalkylamine N-acetyltransferase | - |
Solea senegalensis |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme catalyzes the first step in melatonin biosynthesis, melatonin biosynthesis follows a 24 h day and night rhythm, which is different in fasted, fed, and refed fish, overview | Solea senegalensis |
physiological function | Aanat2 is the main enzyme responsible of the plasma nocturnal melatonin increase in the fish | Solea senegalensis |