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Literature summary for 2.3.1.82 extracted from
- Role of the acetyltransferase AAC(6')-Iz modifying enzyme in aminoglycoside resistance in Stenotrophomonas maltophilia (2003), J. Antimicrob. Chemother., 51, 803-811.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | aac(6')-Iz is an important contributor to aminoglycoside resistance in clinical strains of Stenotrophomonas maltophilia | Stenotrophomonas maltophilia |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| aac(6')-Iz can restore aminoglycoside resistance to tobramycin, netilimicin and sisomicin (four- to eight-fold increase in the MICs) upon Escherichia coli | Stenotrophomonas maltophilia |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Stenotrophomonas maltophilia | aac(6')-Iz can restore aminoglycoside resistance to tobramycin, netilimicin and sisomicin (four- to eight-fold increase in the MICs) upon Escherichia coli | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Stenotrophomonas maltophilia | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | aac(6')-Iz can restore aminoglycoside resistance to tobramycin, netilimicin and sisomicin (four- to eight-fold increase in the MICs) upon Escherichia coli | Stenotrophomonas maltophilia | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AAC(6')-Iz acetyltransferase | - |
Stenotrophomonas maltophilia |
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